一、个人简介

陈科杰，生于1987年9月，四川雅安人，汉族，中共党员，讲师，博士。主要承担《卫生微生物学》的课程教学，从事非编码RNA与肥胖相关疾病的研究工作。

二、教育工作经历

2006.09~2010.06，四川农业大学，动物医学院，动植物检疫检验，获学士学位；

2010.09~2013.06，四川农业大学，动物医学院，基础兽医学，获硕士学位；

2013.09~2017.06，四川农业大学，动物医学院，基础兽医学，获博士学位；

2014.10~2016.10，哈佛医学院/麻省总医院，免疫学，联合培养；

2017.06至今，成都医学院，讲师。

三、主要学术论文（近5年）

1. Guo H, Zuo Z, Wang F, Gao C, Chen K, Fang J, Cui H, Ouyang P, Geng Y, Chen Z, Huang C, Zhu Y, Deng H. Attenuated cardiac oxidative stress, inflammation and apoptosis in obese mice with nonfatal infection of Escherichia coli. Ecotoxicol Environ Saf. 2021, 225:112760.

2. Chen Z, Zuo Z, Chen K, Yang Z, Wang F, Fang J, Cui H, Guo H, Ouyang P, Chen Z, Huang C, Geng Y, Liu W, Deng H. Activated Nrf-2 pathway by vitamin E to attenuate testicular injuries of rats with sub-chronic cadmium exposure. Biol Trace Elem Res. 2021.

3. Fang J, Yin H, Yang Z, Tan M, Wang F, Chen K, Zuo Z, Shu G, Cui H, Ouyang P, Guo H, Chen Z, Huang C, Geng Y, Liu W. Vitamin E protects against cadmium-induced sub-chronic liver injury associated with the inhibition of oxidative stress and activation of Nrf2 pathway. Ecotoxicol Environ Saf. 2021, 208:111610.

4. Wang F, Zuo Z, Chen K, Fang J, Cui H, Geng Y, Ouyang P, Chen Z, Huang C, Guo H, Liu W. Diet-induced obesity mice execute pulmonary cell apoptosis via death receptor and ER-stress pathways after E. coli infection. Oxid Med Cell Longev. 2020, 2020:6829271.

5. Song H, Zuo Z, Yang Z, Gao C, Chen K, Fang J, Cui H, Ouyang P, Deng J, Geng Y, Guo H. Hepatic histopathology and apoptosis in diet-induced-obese mice under Escherichia coli pneumonia. Aging (Albany NY). 2019, 11(9):2836-2851.

6. Wang F, Zuo Z, Yang Z, Chen K, Fang J, Cui H, Shu G, Zhou Y, Geng Y, Ouyang P. Delayed pulmonary apoptosis of diet-induced obesity mice following Escherichia coli infection through the mitochondrial apoptotic pathway. Oxid Med Cell Longev. 2019, 2019:1968539.

7. Wang F, Zuo Z, Chen K, Fang J, Cui H, Shu G, Zhou Y, Chen Z, Huang C, Liu W. Histopathological Changes Caused by Inflammation and Oxidative Stress in Diet-Induced-Obese Mouse following Experimental Lung Injury. Sci Rep. 2018, 8(1):14250.

8. Chen K, Shanmugam NK, Pazos MA, Hurley BP, Cherayil BJ. Commensal bacteria-induced inflammasome activation in mouse and human macrophages is dependent on potassium efflux but does not require phagocytosis or bacterial viability. PLoS One. 2016, 11(8):e0160937.